Spirometry in Smokers and Non-smokers: A Comparative Study

  • Lava Shrestha Institute of Medicine
  • Narayan Bahadur Mahotra Maharajgunj Medical Campus
  • Binaya Shumsher Jung Bahadur Rana Maharajgunj Medical Campus
  • Dinesh Banstola Maharajgunj Medical Campus
  • Tara Man Amatya Nepal Army Institute of Health Sciences
  • Barun Mahat Nepal Army Institute of Health Sciences


Introduction: Spirometry is the physiological test that measures how an individual breathes air volumes as a function of time. Smoking produces an increase in epithelial damage, cellular inflammatory infiltrates, muscles and fibrosis in respiratory airways and is responsible for acute respiratory various illnesses. Early identification of reduction in lung function of smokers by spirometry can be very important in order to encourage them to stop smoking.

Methods: This study included a total of 106 individuals, 51 were smokers and 55 were non-smokers. The participants performed spirometry in the sitting position by open circuit method. Parameters of spirometry FVC, FEV1, FEV1/FVC and PEFR were recorded in the form of a percentage of predicted.

Results: The mean FVC in smokers and non-smokers was 99.98±9.88% and 102.97±8.03% respectively (p=0.092). The mean FEV1 in smokers and non-smokers was 99.65±9.61% and 104.58±10.03% respectively (p=0.011). The mean FEV1/FVC ratio in smokers and non-smokers was 103.25±4.60% and 105.57±5.10% respectively (p=0.016). The mean PEFR in smokers and non-smokers was 102.11±8.40% and 106.01±10.62% respectively (p=0.038).

The mean FVC in smokers was less than in non-smokers (99.98±9.88% and 102.97±8.03%, p=0.092). FEV1, (99.65±9.61% vs 104.58±10.03%, p=0.011) FEV1/FVC ratio (103.25±4.60% vs 105.57±5.10%, p=0.016) and PEFR (102.11±8.40% vs 106.01±10.62%, p=0.038) were significantly lesser in smokers than non-smokers.

Conclusion: The spirometry parameters of pulmonary function were poorer in the smoker group. Spirometry can be useful in detecting a reduction in pulmonary function before the appearance of any symptoms or before pulmonary functions become significantly abnormal.

Keywords: COPD, FEV1, FVC, PEFR, pulmonary function test, smoking, spirometry

DOI: https://doi.org/10.3126/jkahs.v2i3.26661

How to Cite
Shrestha L, Mahotra N, Rana B, Banstola D, Amatya T, Mahat B. Spirometry in Smokers and Non-smokers: A Comparative Study. JKAHS [Internet]. 6Dec.2019 [cited 25Feb.2020];2(3):234-8. Available from: https://www.jkahs.org.np/jkahs/index.php/jkahs/article/view/137